PhD Candidate in Science and Technology for Advanced Therapies 

I graduated with honours in Biotechnology (BSc) and in Molecular Biology and Genetics (MSc) at the 
University of Pavia. My early research interests were focused on genomics, which led me to carry my BSc internship at the Molecular and Cellular Biology Laboratory under the supervision of Professor Elena Giulotto. For my bachelor’s thesis, I investigated the expression profile of subtelomeric loci in human cell lines, aiming to explore the transcriptional activity of telomeric regions, strongly implicated in genome stability and aging. 
Over time, my attention shifted toward a more proteomic and structural biology perspective, which I found 
to be better aligned with my interests. During my MSc internship at the Structural Biology Laboratory of Professor Andrea Mattevi, I worked on the biochemical and structural characterization of the mycobacterial protein CpsA and its interaction with human NADPH oxidase 2 (NOX2), a key component of the innate immune response. The project aimed to elucidate a novel immune evasion strategy employed by Mycobacterium tuberculosis, contributing to a deeper understanding of NOX2 regulation. 
My current PhD project, supervised by Professor Andrea Mattevi, focuses on investigating how enzymes of 
the kynurenine pathway are organized and interact within cells, and how their activity and interactions change in response to different cellular conditions. Given the central role of this pathway in cancer, this work aims to clarify its regulation directly in a cellular context.